1-乙炔基环己醇

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1-乙炔基环己醇
识别
CAS号 78-27-3  ✓
SMILES
性质
化学式 C8H12O
摩尔质量 124.18 g·mol−1
密度 0.9809 g·cm−3(20 °C)[1]
熔点 30 °C(303 K)[2]
31~32 °C(304~305 K)[3]
沸点 179 °C(452 K)[3]
若非注明,所有数据均出自一般条件(25 ℃,100 kPa)下。

1-乙炔基环己醇是一种有机化合物,化学式为C8H12O,它可由乙炔环己酮氢氧化钾的存在下于DMSO中反应制得。[4]它和乙酸酐反应,生成乙酸-1-乙炔基环己酯。[5]它和有机叠氮化物反应,乙炔基转化为三唑。[6]

参考文献[编辑]

  1. ^ Levina, R. Ya.; Vinogradova, E. I. Action of sodium acetylide on cyclic ketones. I. Synthesis of 1-​ethynylcyclohexanol. Zhurnal Prikladnoi Khimii (Sankt-Peterburg, Russian Federation), 1936. 9: 1299-1302. ISSN: 0044-4618.
  2. ^ Verkruijsse, Hermann D.; Graaf, Wim de; Brandsma, Lambert. An Efficient and Quick Laboratory Scale Method for the Ethynylation of Some Aliphatic and Cycloaliphatic Carbonyl Compounds. Synthetic Communications. 1988, 18 (2): 131–134. ISSN 0039-7911. doi:10.1080/00397918808077336. 
  3. ^ 3.0 3.1 Nazarov, I. N.; Kotlyarevskii, I. L.; Ryabchenko, V. F. Acetylene derivatives. CLX. Condensation of aldehydes and ketones with acetylene under pressure. New method of synthesis of acetylenic alcohols. Zhurnal Obshchei Khimii, 1953. 23: 1900-1904. ISSN: 0044-460X.
  4. ^ Trofimov, B. A.; Sobenina, L. N.; Korostova, S. E.; Mikhaleva, A. I.; Shishov, N. I.; Fel'dman, V. D.; Shevchenko, S. G.; Vasil'ev, A. N. Synthesis of tertiary acetylenic alcohols and their ethers in a potassium hydroxide-​dimethyl sulfoxide system. Zhurnal Prikladnoi Khimii (Sankt-Peterburg, Russian Federation), 1987. 60 (6): 1366-1370. ISSN: 0044-4618.
  5. ^ D'Elia, Valerio; Liu, Yinghao; Zipse, Hendrik. Immobilized DMAP Derivatives Rivaling Homogeneous DMAP. European Journal of Organic Chemistry. 2011, 2011 (8): 1527–1533. ISSN 1434-193X. doi:10.1002/ejoc.201001507. 
  6. ^ Heriberto Díaz Velázquez, Yara Ruiz García, Matthias Vandichel, Annemieke Madder, Francis Verpoort. Water-soluble NHC-Cu catalysts: applications in click chemistry, bioconjugation and mechanistic analysis. Org. Biomol. Chem. 2014, 12 (46): 9350–9356 [2020-08-31]. ISSN 1477-0520. doi:10.1039/C4OB01350F (英语).